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Volpe S, Lisco G, Fanelli M, Racaniello D, Colaianni V, Triggiani D, et al

Adipose-derived inflammation contributes to systemic low-grade inflammation through the release of cytokines such as TNF-, IL-6, and IL17, which can exacerbate keratinocyte activation and immune dysregulation in psoriatic skin

Someone with a blunted receptor may need a more tailored, personalised approach

Credits: Pharmaceutical Network group

Cureus 11 , e5810 (2019)
