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In pooled analyses of randomised controlled trials, participants treated with retatrutide experienced a higher frequency of hypersensitivity events compared with placebo
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Furthermore, lean T2D patients have higher levels of fasting ghrelin, whereas obese T2D subjects have lower levels of fasting ghrelin, than do normoglycemic lean control subjects (26)

[DOI] [PubMed] [Google Scholar] 80.Ravcheev D.A., Godzik A., Osterman A.L., Rodionov D.A