allodynia and semaglutide is being reported with GLP-1 medications, It is a heightened sensitivity to touch that can feel like pain. We are seeing it more at higher doses, The important point is that it appears Skin reactions (allodynia) long term
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From the data in this study, our team created these charts

Some people who experienced injection site burning or redness with tirzepatide find that semaglutide causes less irritation, while others experience the opposite

The correlation between insulin and PDA is a reciprocal self-reinforcing relationship

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Astrup A, Rossner S, Van GL, Rissanen A, Niskanen L, Al HM et al