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The frequency category in UK SmPCs for losartan products (such as those listed on the MHRA's Electronic Medicines Compendium) may be recorded as 'rare' (fewer than 1 in 1,000 patients) or, in some product listings, as 'frequency not known' reflecting that the evidence comes largely from spontaneous case reports rather than controlled clinical trials

Most users begin to experience reduced cravings and improved appetite control within the first 2 to 4 weeks

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95% CI 0.69, 0.92) [25] was maintained irrespective of the initial glomerular filtration rate [30]

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Additionally, GLP-1 agonists influence gastric emptying, which could interact with psychiatric medication pharmacokinetics, altering their effectiveness or safety, especially those with weight-based dosing