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For someone weighing 220 pounds, 15% weight loss means losing approximately 33 pounds over about 16 months
Cognitive effects of low-dose topiramate compared with oxcarbazepine in epilepsy patients

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The FDA-approved Wegovy prescribing information discloses that in the SELECT cardiovascular outcomes trial, hip and pelvis fractures occurred more often in female patients on Wegovy than on placebo (1% vs