gastric bypass vs glp 1 Bariatric Surgery vs. GLP-1 Medications: What the Latest Research Shows The role of GLP-1 in

Other research highlights: 30% of GLP-1 users tested positive for SIBO or IMO even after accounting for diabetes (5) GLP-1 medicines caused microbiome changes and altered metabolism in mice (6) GLP-1 medicines tested in humans only had noticeable microbiome changes by 48 weeks (7) Despite not necessarily having slower gut motility, one study found that 88.9% of obese patients had SIBO (8) A meta analysis of people with IBS symptoms, found that up to 78% of people had SIBO, many of whom were undiagnosed (9) Overall, Sun and colleagues (1) could not prove a mechanistic link between GLP-1 medications and SIBO, however they did find that SIBO was twice as likely in GLP-1 users

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These drugs have shown efficacy beyond glycaemic regulation, including significant weight loss, cardiovascular protection, and possible advantages for renal function

GLP-1RAs have been found to modulate the pathogenesis and progression of migraine by attenuating neuroinflammation and suppressing neuronal hyperactivity [94, 95]

In someone with diabetes, a clinician may also ask about recent glucose trends, appetite, fluid intake, and whether ketones have been checked before

Bring the PACE plan and the verify checklist to your next appointment so your clinician can tailor targets to you