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Many reports showed that GLP-1 effects involve neural modulation and peripheral effects, which increase satiety, resting energy expenditure and lower plasma concentrations of free fatty acids [20]-[22]

If a dose is missed, administer it as soon as possible, provided it is within 4 days of the scheduled injection day

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Further evidence supporting this hypothesis comes from the typical decrease in bone turnover observed after oral glucose intake, which is inhibited by infusion of octreotide, a somatostatin analog that suppresses the secretion of gastrointestinal and pancreatic peptides [43]

This allowed us to investigate the effects of the combination of native amylin and GLP-1 therapy on the intake suppressive effects in the first meal