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On a U-100 syringe, 1 mL = 100 units, so multiply mL by 100: 0.10 mL 100 = 10 units So the documented 0.25 mg starting dose is a 10-unit draw a small, easy-to-read mark near the bottom of the barrel

There is no evidence that one timing is superior to the other pharmacologically, so choose what works for your schedule and tolerance

10.2147/IJN.S479670

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There are limited drugdrug interactions and no dosing adjustments in patients with upper gastrointestinal disease, renal impairment or hepatic impairment

The most common side effects are gastrointestinal, including nausea, vomiting, and diarrhoea, and are most pronounced during dose escalation