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Research Highlights: The weight loss medication tirzepatide significantly lowered the systolic blood pressure of nearly 500 adults who had obesity and took the medication for 36 weeks, or about eight months, in a subset of an international clinical...

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This article explains their mechanisms, biomarker factors that may influence effectiveness, and why medical provider oversight is essential for safe, personalized use
The regulation of energy homeostasis by centrally-produced GLP-1 is not yet fully understood

In insulin-treated patients, disordered gastric emptying, even when not associated with gastrointestinal symptoms, can cause a mismatch between the onset of insulin action and the availability of absorbed carbohydrate, leading to suboptimal glycaemic control
