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(3) Diuretics can also cause hyperglycemia, hence may diminish blood sugar control in patients with high blood sugar placed on semaglutide

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After years of development, a synthetic version of exendin-4, known as exenatide and marketed as Byetta, was approved by the FDA in 2005

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Multivariate analysis of fasting glucose showed that fasting glucose was lower in the placebo arm at 12 months (2.2 mmol/L 95%CI: 0.4, 4.1, p = 0.027) but not at 6 months (1.4 mmol/L, 95%CI 1.1, 3.9, p = 0.24) (Supplementary Tables 10.1 and 10.2)