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Additional symptoms that warrant medical attention include: Nausea and vomiting , particularly when associated with abdominal pain Fever and chills , which may indicate cholecystitis or infection Jaundice (yellowing of skin and eyes), suggesting bile duct obstruction Clay-colored stools or dark urine , indicating impaired bile flow Persistent indigestion or bloating, especially after fatty foods Acute cholecystitis presents with more severe symptoms, including persistent right upper quadrant pain lasting more than six hours, fever above 100.4F (38C), and a positive Murphy's sign (inspiratory arrest during right upper quadrant palpation)

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