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Semaglutide, a GLP-1 receptor agonist originally developed for type 2 diabetes, has gained attention for modest weight loss results in people seeking to shed 10 pounds or more

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Someone starting at 300 pounds losing the same 30 pounds represents 10% reduction and often occurs in 46 months on semaglutide or 35 months on tirzepatide

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There were no apparent differences in any of the other pharmacokinetic parameters between the 2 treatment periods

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Dosing starts at 2.5 mg weekly and escalates to a maintenance dose of 10 mg or 15 mg weekly

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Less serious side effects may also occur, including nausea, vomiting, diarrhea and constipation, according to Harvard Health

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