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In addition, some aspects of GLP-1 beyond weight loss, such as preclinical evidence on GLP-1 effects in directly modulating the hypothalamuspituitarygonadal axis, or the effects of GLP-1RA on clinical and biochemical expression of hyperandrogenism, still deserve a greater insight, especially in light of a possible therapeutic use in PCOS women independently of obesity

Many patients see meaningful results at this dose, though maximum effects typically emerge at higher maintenance levels

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Clinical trials demonstrate that GLP-1 receptor agonists like semaglutide can help lower systolic and diastolic readings while promoting metabolic health

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