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doi: 10.5498/wjp.v8.i5.114
First cardiovascular safety trial to demonstrate that a GLP-1R agonist reduces MACE and microvascular (including renal) events in patients with T2DM and high cardiovascular risk
GLP-1 agonists do not affect contraception methods that arent pills
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These agents are based on the gut-derived incretin hormone GLP-1, which is a potent stimulator of insulin, while suppressing glucagon secretion (2)
That underperformance relative to the broader drug sector is part of what makes the case compelling to BofA
