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Slow and steady discontinuation Stopping GLP-1 medications abruptly may lead to rapid weight regain

Patients who make appropriate dietary modifications early in treatment may experience improved tolerability

In 1992, Eng et al

Safety Considerations and Who Should Have This Conversation with Their Provider GLP-1 medications are not suitable for everyone, and individual tolerability conversations should include assessment of personal medical history, current medications, and baseline gastrointestinal health

Not necessarilymild nausea is normal and often decreases after the first few weeks regardless of timing

This can make it even harder to maintain strength, metabolism, and physical activity during and after GLP-1 treatment