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These agents have been demonstrated to improve renal function by attenuating eGFR, reducing albuminuria, and decreasing oxidative stress

5.3 GIP and GLP-1 effects on gastric emptying The secretion of endogenous GIP does not correlate with gastric half-emptying times (150)

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It's also adhesions, organ tethering, scar tissue, thickened tissue, uh, pain that gets worse over time because of how things are pulling on the structures