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As interest in addressing the multifaceted pathophysiology of MASLD expands, the potential of tirzepatide to improve insulin sensitivity, promote weight loss, and modify hepatic inflammation makes it an attractive candidate for further investigation

Patients should avoid injecting into the same spot repeatedly and maintain a rotation schedule, waiting at least one week before returning to a previously used site

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Tirzepatide shows remarkable kidney-protective effects across multiple patient populations

These results are similar to those of Azzam et al., 17 who found that GLP-1 RAs contributed to a 72% decrease in blindness or visual abnormalities at 3 months with long-lasting advantages at 24 months

Alchirazi KA, Baliss M, El Telbany A, et al