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The American Society of Anesthesiologists recently released a consensus-based guideline recommending holding [glucagon-like peptide-1 receptor agonists (GLP-1RAs)] before an endoscopic or surgical procedure to decrease the risk of aspiration, Yee Hui Yeo, MD, a resident in the Karsh Division of Gastroenterology and Hepatology at Cedars-Sinai Medical Center in Los Angeles, and colleagues wrote in Gastroenterology

Current clinical consensus reflects the following: Research findings are preliminary and insufficient to guide treatment decisions No regulatory approval exists for using GLP-1s in addiction treatment Early signals do not outweigh the lack of long-term outcome data Instead, clinicians continue to recommend established, evidence-based approaches, including: Behavioral therapies tailored to substance use disorders Medication-assisted treatment when medically indicated Comprehensive psychosocial support and relapse-prevention planning Comprehensive assessment remains a cornerstone of safe and effective care

Additionally, you should integrate lifestyle changes that can protect your muscle mass and bone density

Quick Answer: Weight loss may stall on Zepbound due to metabolic adaptation, insufficient time on therapeutic doses, underlying medical conditions, medication interactions, or lifestyle factors that counteract the medication's appetite-suppressing effects

However, it can also impact blood sugar levels and nutrient absorption, ultimately leading to hypoglycemia, malnutrition and other serious side effects

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