glp 3 same as retatrutide vs. Ozempic: The Triple Agonist That May Change Everything., Semaglutide hits one receptor. Retatrutide hits three., That difference may be the biggest leap in metabolic medicine since , GLP-1? Helpful. GLP-2? Amazing. GLP-3?

Variants in GLP1R (the GLP-1 receptor itself), GIPR (the GIP receptor that tirzepatide also activates), FTO (appetite regulation), MC4R (satiety signaling), and TCF7L2 (insulin response) are associated with measurably different response patterns to semaglutide and tirzepatide

References: Rubino, D., Abrahamsson, N., Davies, M., Hesse, D., Greenway, F

Well-tolerated options: Steamed zucchini, roasted sweet potatoes, sauteed spinach, cooked carrots, roasted bell peppers, and mashed butternut squash Introduce raw vegetables gradually: As your body adjusts to the medication, you can slowly reintroduce raw salads and crudites

Never freeze: Freezing destroys the peptide structure and renders it inactive

Abbreviations AD: Alzheimers disease CCK: Cholecystokinin CNS: Central nervous system CRF: Corticotropin-releasing factor DPP4i: Dipeptidyl peptidase-4 inhibitor FDA: Food and Drug Administration FOS: Fructooligosaccharides GERD: Gastroesophageal reflux disease GI: Gastrointestinal GIP: Glucose-dependent insulinotropic polypeptide GLP-1: Glucagon-like peptide-1 GLP-1 RA: Glucagon-like peptide-1 receptor agonist IPPW: Isolated pyloric pressure wave MMC: Migrating motor complex PYY: Peptide YY RCT: Randomized controlled trial SCFA: Short chain fatty acid T2DM: Type two diabetes mellitus References Yao H, et al

Anti-inflammatory effects that matter for autoimmune conditions A growing body of research suggests that GLP-1 receptor agonists have significant anti-inflammatory properties independent of weight loss