can semaglutide cause sleepiness Does Fatigue? Managing Energy Why Semaglutide Makes You Tired:

Expanded Indications for GLP-1 Receptor Agonists The 2025 American Diabetes Association (ADA) Standards of Care have broadened the use of GLP-1 receptor agonists beyond glycemic control

Sharma AK, Khandelwal R, Wolfrum C

For example, insurance coverage may also influence treatment patterns

SGLT-2 inhibitors may adversely affect muscle mass, contributing to an increased risk of sarcopenia in frail individuals

If your thyroid function tests (TSH and free T4) show changes after starting GLP-1 therapy, your levothyroxine dose may need adjustment

In addition, GHSR agonists can provide relief to diabetic individuals experiencing nausea and vomiting as a result of gastroparesis [161,162,163,164]