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Our findings suggest that changes in DWI-MRI in individuals with type 2 diabetes without CKD may reflect other changes in kidney microstructure than fibrosis

A Phase 1 First-in-Human study in healthy volunteers is currently underway with safety data expected at the end of this year

( Epub 2016/03/20 )
For empagliflozin background, Empagliflozin Uses explains where this SGLT2 inhibitor fits in type 2 diabetes care

They also signal in key brain areas involved in appetite, motivation, and reward
