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Change in HbA1c from baseline to 1 year was a second primary outcome for adults with prediabetes at baseline

Phentermine/Topiramate ER Only one small trial has evaluated this combination in a PCOS population, comparing phentermine 7.5 mg plus topiramate 46 mg ER daily to exenatide 2 mg OW ( n = 36 for both arms) [171]

Its essential to lose weight gradually, eat adequate protein, calcium, and vitamin D, and engage in weight-bearing exercise

As a tablet, it eliminates the need for injections, making it more accessible and convenient for individuals who may have aversions or fear of needles

The funds will also be used to advance several first-in-class programs and establish a clinical trial manufacturing facility

Insulin resistance is associated with metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as NAFLD), polycystic ovary syndrome (PCOS), obstructive sleep apnea, and certain metabolic-related conditions