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doi: 10.4103/1673-5374.332122

Natural Supplements Certain supplements may support GLP-1 activity and metabolic function: Berberine Mimics some effects of GLP-1 and supports insulin sensitivity

And just like the proteins in food, it's sensitive to its environment

Reference: Paggers L, Mesotten D, Stragier H

Tirzepatide has a dual-receptor action, targeting both GLP-1 and GIP, which leads to more significant weight loss compared to Semaglutide, which only targets GLP-1

Tesamorelin is not a conventional weight loss medication and should not be viewed as a substitute for Wegovy, Ozempic, semaglutide, tirzepatide, or other GLP-1 treatments