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The South African Health Products Regulatory Authority (SAHPRA) and the South African Pharmacy Council (SAPC) have ramped up a nationwide crackdown on the illegal manufacturing and supply of unregistered weight-loss medicines.

GLP-1, like many other small peptides, is commonly produced through chemical synthesis, but is limited by cost and product quantity

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Based on a systematic synthesis of available findings, we conclude that there is considerable support for the neuromodulatory potential of gut-based circulating peptides on reward responses

Here is what the evidence says about protecting your bones and muscle on GLP-1 therapy.