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( 10.1016/j.cmet.2019.01.004) [DOI] [PMC free article] [PubMed] [Google Scholar] 96.American Diabetes Association

The vagus nerve is extraordinarily sensitive to local gut hormone concentrations, and it does not require supraphysiological levels to fire

Avoiding ultra-processed foods and refined carbohydrates

Changes reflect the placebo-subtracted effect

General eligibility criteria per brand disclosure include BMI 30, or BMI 27 with at least one qualifying comorbidity

Institutional Review Board Statement The study was conducted according to the guidelines of the Declaration of Helsinki and approved by the Ethics Committee of CSIC (protocol code 115/2017) and the Ethics Committee of Hospital Universitario Puerta de Hierro-Majadahonda (code 156-17, Acta 08.18)