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Glucagon-like peptide-1 regulates brown adipose tissue thermogenesis via the gut-brain axis in rats

The stained cells were then examined using a Zeiss AxioCam, CCD camera attached to the Zeiss Axiovert 200 M inverted microscope with fluorescence/phase or DIC imaging (Carl Zeiss Light Microscopy GmbH, Gottingen, Germany) and processed with MetaMorph Software (Molecular Devices Inc., Sunnyvale, CA)

In addition, another study also confirmed the expression of GLP-1 receptors in PTC and the expression rate of GLP-1 receptors in PTC, which was almost 30% (69)

Potential rebound: Abrupt discontinuation, even from low doses, may cause appetite rebound and metabolic slowdown
Ebbing A, Vrtesy , Betist MC, Spanjaard B, Junker JP, Berezikov E, van Oudenaarden A, Korswagen HC (2018) Spatial transcriptomics of C

Oral versions offer convenience for patients who travel frequently or dislike needles, though injectable forms typically reach therapeutic levels faster and may require lower total doses
