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Specifically, a lot of patients say that they seem to struggle with the accumulation of belly fat in their midsection more than any other area of the body
This increase is believed to reflect the bodys natural hormone production recovering as weight and insulin resistance improve
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Similar content being viewed by others Introduction Glucagon-like peptide-1 (GLP-1) is a gut-derived hormone that plays a crucial role in glucose metabolism and insulin secretion

Phase 3 Update: TRIUMPH-4 Results Preliminary data from the ongoing Phase 3 TRIUMPH-4 trial (68 weeks) shows higher numbers than Phase 2: 12mg dose: 28.7% average weight loss (~71 lbs / 32 kg) 9mg dose: 26.4% average weight loss (~64 lbs / 29 kg) Knee osteoarthritis pain: 76% reduction (significant quality-of-life improvement) Blood pressure: Average reduction of 14 mmHg Full Phase 3 results across the TRIUMPH program (obesity, diabetes, cardiovascular outcomes, kidney outcomes) are expected throughout 2026

Heather JL, Nadine SC, Richard DM, Wayne WC