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Why Immunogenicity Matters for GLP-1 Peptide Drugs Peptide-based therapeutics inherently carry a higher immunogenic risk than small molecules due to their size, sequence complexity, and structural similarity to endogenous proteins

The pivotal STEP 1 trial, published in The New England Journal of Medicine in February, included 1,961 adults without diabetes who had obesity or overweight with a weight-related comorbid condition

Social media also strongly influenced how people viewed weight loss medications, often shaping expectations more than medical guidance

10.1172/JCI186426 J Clin Invest

The NPI is a unique identifier essential for verifying the prescriber's credentials and processing the request

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