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GLP-1 Drugs Affect Your Gut and Brain These medications also enhance insulin secretion, which can result in better blood sugar control in addition to weight loss, says Sara Velayati, MD, an obesity medicine specialist at Montefiore Einsteins Fleischer Institute Medical Weight Center in New York

This is less common when GLP-1 medications are used alone

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For more on the overall treatment experience, see our overview of GLP-1 side effects in 2026

The difference is small enough that consistency matters more than timing
