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Today we announced positive topline results from the first Phase 1b clinical trial of elecoglipron conducted in China in adults living with obesity/overweight, with or without type 2 diabetes

This review synthesizes current evidence on glucagon-like peptide-1 receptor agonists (GLP-1 RAs), a well-studied AOMs, focusing on their effects on sarcopenia through mechanistic insights and clinical considerations in older adults

The proportion of patients who discontinued the treatment due to AEs was 3%

Over the past 4 decades, obesity has escalated into a global epidemic, with its worldwide prevalence nearly tripling

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reduced form)-dependent buffering systems, several constraint-sensitive metabolic processesincluding NAD partitioning, amino aciddependent antioxidantanabolic coupling, micronutrient-dependent enzymatic activity, and bile acidmediated absorptionmay become functionally limiting