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Consequently, GLP-1 that is secreted by intestinal L-cells is rapidly degraded by dipeptylpeptidase-4 (DPP-4) in the endothelium of the portal circulation and in the liver, as well as by a soluble circulating moiety of DPP-4

For patients on Ozempic experiencing hiccups, start with metoclopramide 10-20 mg orally or IV every 4-6 hours as first-line therapy, or alternatively use bac...

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