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One of the key players in this complex system is GLP-1 (Glucagon-like peptide-1) , a hormone produced in the gut that has profound effects on both metabolism and longevity
The potential for a well-known medication to provide a new treatment option could change how alcohol use disorder is managed

In PIONEER-4 study, oral semaglutide was non-inferior to subcutaneous liraglutide and superior to placebo in reducing HbA1c level, and superior in reducing body mass compared with both liraglutide and placebo at week 26

Tirzepatide is a dual GLP-1 + GIP receptor agonist

Nilotinib is approved under the brand name Tasigna, which is owned and marketed by Novartis, and is indicated for Philadelphia chromosome-positive chronic myeloid leukemia
