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A randomized controlled trial found that carrageenan, a common food additive, may cause subclinical inflammation and insulin resistance in overweight individuals, mediated by gut permeability and inflammation

GLP-1, a hormone secreted by the intestines, lowers blood glucose and promotes weight loss through multiple mechanisms: it enhances insulin secretion in a glucose concentration-dependent manner, suppresses glucagon release, delays gastric emptying, and reduces food intake via central appetite suppression

Monitoring of blood sugar lipid profile liver function and overall metabolic health is advised

Chronic knockdown of LH GLP-1R induced by intraparenchymal delivery of an adeno-associated virus-short hairpin RNA construct was sufficient to markedly and persistently elevate ingestive behavior and body weight and ultimately resulted in a doubling of fat mass in males and females

Due to a short plasma half-life of native GLP-1, several synthesized GLP-1 receptor agonists (RAs) were developed for type 2 diabetes mellitus (DM) treatment

Although the reaction was sudden onset, it did not meet the Brighton Criteria of anaphylaxis