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The 2025 review also reported that in a large retrospective study of 461,328 adults initiating GLP-1 therapy, over 22% developed at least one nutritional deficiency within 12 months, with vitamin D the most common deficiency identified

Doupis et al

[DOI] [Google Scholar] 67.Ben-Shlomo S., Zvibel I., Varol C., et al

25:226-234 [PubMed: 36377106] 181

Phentermine triggers the release of norepinephrine in the brain, and to a lesser extent dopamine and serotonin

You may be a suitable candidate if you: Have a BMI over 30 (or over 27 with weight-related health issues like high blood pressure, diabetes, or other cardiovascular risk factors) Struggle with food cravings and portion control Have insulin resistance or prediabetes Are looking for a long-term weight loss solution without dangerous side effects These medications are not a quick fix, but they provide lasting results when paired with healthy lifestyle habits
