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Changes in HbA1c and body weight were generally similar across insulin regimen subgroups, without significant treatment interactions by subgroup, and the total daily insulin dose was decreased for patients receiving oral semaglutide

Semaglutide is FDA-approved for obesity at BMI 30+, but doctors may prescribe it off-label for lower BMIs when other health factors apply

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The EMAs Pharmacovigilance Risk Assessment Committee (PRAC) that monitors side effects of pharmaceuticals, will examine a "signal of aspiration and pneumonia aspiration" associated with GLP-1 receptor agonists (GLP-1 ra).The move follows a June 2023 announcement by the American Society of Anesthesiologists (ASA) that

These compounds collectively provide researchers with tools for investigating incretin receptor biology, metabolic signaling integration, and endocrine pathway regulation