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In light of this potential significant safety issue, the development of Lotiglipron has been discontinued, meaning the drug did not progress to further clinical trial stages to evaluate its efficacy and safety

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doi: 10.1016/j.japh.2019.11.008

Experts soon learned that, in addition to improving blood glucose levels and A1C for diabetes care, GLP-1s also brought about significant weight loss and other metabolic health benefits
