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retatrutide phase 2 obesity nejm 2023 jastreboff In patients with #obesity, incretin-based therapies such as GLP-1 receptor agonists are reported to result in mean weight reductions of approximately 15 to 20% along with additional health benefits, including decreased cardiovascular Retatrutide, an Amazing Future for
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Abstract Introduction Obesity and type 2 diabetes mellitus (T2D) increase the risk of kidney disease

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Antonosante, A
The program includes several active studies: TRIUMPH-1 : adults with obesity, no diabetes TRIUMPH-2 : adults with obesity and Type 2 diabetes TRIUMPH-3 : adults with obesity and cardiovascular disease TRIUMPH-4 : adults with obesity and knee osteoarthritis Additional studies in obstructive sleep apnea and MASLD Top-line readouts from the obesity studies are widely expected through 2026 and into 2027
