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Lonizable lipid NPs (LNPs) dominate current GLP-1R-targeted formulation research because their head group pKa can be matched to endosomal pH, driving a cone-shape flip that destabilizes the vesicle membrane and improves cytosolic release [115]
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Hum Reprod 33(9):16021618

Gut microbiota determines the fate of dietary fiber-targeted interventions in host health
