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[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Hysenaj F, Lauber M, Bast-Habersbrunner A, List M, Klingenspor M (2024) Single-cell transcriptome analysis reveals secretin as a hallmark of human enteroendocrine cell maturation

Pemvidutide and survodutide are both GLP-1/glucagon dual agonists being developed for obesity and MASH, but survodutide is further ahead in clinical development with more advanced Phase 3 programs, higher-tier regulatory designations (Breakthrough Therapy vs Fast Track), and greater weight loss in Phase 2 (18.7% vs 15.6%)

Class 1 = Recommendation is indicated/useful/effective/beneficial

Ahrn B, Masmiquel L, Kumar H, et al

Liraglutide-induced increases in the microtubule-associated protein 1A/1B-light chain 3 (LC3)-II expression and p62 degradation were prevented by the compound C-mediated inhibition of AMPK
