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The battle over America's booming weight-loss drug market has a significant update, with a move thats likely to cause a shift across the healthcare and corporate benefits landscape: Cigna, one of Americas biggest insurers, is dropping coverage for GLP-1 obesity drugs, even for its own staff
Glucagon-like peptide-1 (GLP-1s) agonists have recently made headlines as a potential tool to address substance use disorder.

Here, we report three cryo-electron microscopy structures of GLP-1R bound to (i) compound 2 (an ago-allosteric modulator)

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