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Diminished insulin secretion in response to treatment with GLP-1 has been replicated in other studies [[560], [561], [562]]

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Add GLP1 side effects on top

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More serious but rare risks include pancreatitis and gallbladder disease

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Follow-up: Minimum follow-up duration of 6 months

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The important signalling role of these hormones in the brain for obesity and type 2 obesity had been first flagged up following the discovery of leptin and later ghrelin

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