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If you cannot reliably determine how long the pen has been left out of the fridge, or if it has been exposed to extreme temperatures (either freezing or heat above 30C), it is safer to discard the pen and use a new one
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Do not use GLP-1 medications if you or your family have a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Diabetes 65 , 172187 (2016)

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