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Beyond these metabolic benefits, accumulating evidence indicates that GLP-1RAs exert immunomodulatory effects, including suppression of pro-inflammatory cytokines, enhancement of regulatory T-cell function, and improvements in adipose tissue and gut-derived immune signaling

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We also present practical implications of these glucose-lowering agents for reducing the risk of adverse cardiovascular events and progressive renal comorbidity in patients with T2D and CVD.

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