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Overuse in Non-Clinical Cases Some individuals are using GLP-1s without meeting current medical guidelines, creating potential for misuse or overuse and perpetuating an unrealistic standard of thinness

Continued support for dietary and exercise changes is essential for maintaining weight loss achievements

Kidney Failure: People who already have kidney problems have more risk, especially if they get dehydrated

Their nervous systems are more reactive

As Tigress Osborn, executive director of the advocacy organization the National Association to Advance Fat Acceptance, explains, it's "harder to be in the world as a fat personespecially as a very fat person," she tells Fortune

While drug developers work to mitigate the side effects associated with GLP-1based obesity drugs, recent studies reveal that myriad variables are causing patients to stop treatment