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Description
Ex vivo preparations of pancreatic or gastrointestinal tissue to assess hormone release and motility under controlled conditions

ITCA 650 is a subcutaneously implanted matchstick-sized osmotic mini-pump, which continuously releases exenatide for 6 months in a zero-order manner, making twice-yearly administration possible [98]

Obes Surg [Internet]

You already have maximum GLP-1 activity from the shot, and extra fiber may worsen nausea

GLP-1 also helps slow down digestion

They may alleviate certain IBS problems (like urgency, pain, bloating) thanks to slower motility and gut-level effects