which glp-1 agonists have cardiovascular benefit View of Diabetes medications with protection after HARMONY Outcomes and DECLARE-TIMI 58: could metformin, pioglitazone, SGLT2 inhibitors and long-acting receptor complement each other to save lives by different mechanisms? The cardiovascular effects of GLP-1

[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Jeek P, Holendov B, Jabrek M, et al

Ann Pharmacother

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This analysis reveals a greater degree of engagement of tirzepatide for the GIP receptor than the GLP-1 receptor, corroborating an imbalanced mechanism of action