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Within this framework, incretins particularly glucagon-like peptide-1 (GLP-1) have emerged as key immunometabolic regulators rather than merely glucose-lowering hormones

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However, many of these effects occurred at doses that also caused significant maternal weight loss, making it difficult to determine whether the medication itself or the weight loss caused the problems

Lamos et al., 2017)

The trade-off is that post-marketing reports don't always prove causation, people may be taking multiple medications, may have diabetes-related neuropathy, or may have developed a new condition unrelated to the drug

The courts upcoming rulings on expert testimony are expected to shape which claims proceed toward bellwether trials