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FIB-4 demonstrates a high negative predictive value (NPV 90%) for excluding advanced fibrosis, supporting its role as an effective first-line screening tool

In the double-blind, placebo-controlled ATTAIN-1 trial, continuous use of the highest dose of Foundayo led to an average weight loss of 12.4% (27.3 pounds) after 72 weeks, compared with 0.9% (2.2 pounds) with placebo

The future of colorectal cancer prevention is likely to be integrated, metabolic, and personalized, reflecting a deeper understanding of cancer as a systemic disease

It is a structural analogue of human glucagon-like peptide 1 (GLP-1), which can mimic its effect, reduce hunger, reduce diet, and reduce calorie intake

GCG activation suppresses endogenous hepatic lipid production by inhibiting lipogenic enzymatic pathways while simultaneously enhancing mitochondrial oxidative lipid catabolism, thereby promoting lipid catabolism and reducing hepatic triglyceride content [18]

Liraglutide paved the way for GLP-1 therapies in obesity treatment, but most patients and clinicians now prefer semaglutide or tirzepatide because of stronger results and easier dosing