liraglutide glp 1 agonist is a GLP-1 Receptor for Type 2 Diabetes Research GLP-1 receptor agonists | How

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doi:10.1016/j.mam.2018.11.001 62

2 The APA article notes that many patients discontinue treatment within a year because of side effects, cost, access issues, or other challenges, but this source does not establish mental distress as a uniform or primary reason across all patients

406,407 Furthermore, astrocytes express GLP-1R, which has been found to be crucial for their proper functioning

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Binding to this allosteric site can still influence the sensitivity and activity of the receptor, but could lead to drugs with fewer off-target side-effects, since GLP-1 is involved in many different metabolic signalling pathways