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Itchy, watery eyes are one of the best indicators of allergies versus sinus infections

Monitoring urine color (aiming for pale yellow) provides a simple assessment of hydration status

This ritualistic aspect improves adherence because the injection becomes embedded in a calming evening routine rather than feeling like an interruption to a busy morning

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While mild anxiety is a recognized indirect effect of tirzepatide, severe mental health symptoms warrant a comprehensive assessment and potentially a referral to a psychiatrist who can evaluate the interaction between the medication and mental health

Do not obsess over minor day-to-day variations